Published on : Dec 02, 2019
African Trypanosomiasis is popularly known as sleeping sickness and is primarily prevalent in African regions. Tsetse flies that exist in this regions are identified as the vectors of African Trypanosomiasis and the disease undergoes cyclic development here. Tsetse flies exclusively exist in these specific regions of Africa owing to the favorable environmental conditions such as humidity and temperature.
Some verities of trypanosome are infect animals and cattle. This disease is known as nagana which adversely affect the annual productivity every year. A healthy tsetse fly acquires trypanosomiasis form infected vertebrae. On biting these vertebrae, the infected blood reaches there mid gut trough esophagus. These infecting organisms initiate their procyclic stages in mid gut and undergo differentiation in various parameters that include biochemical and morphological composition. The lifecycle of trypanosomes is very complex and their vectors have the least changes of getting infected form them. An array of factors including age, blood meal, genotype and sex of the vectors determines susceptibility of tsetse flies.
An intelligence report titled, “African Trypanosomiasis-Pipeline Review, H2 2019” is the source of all the stated insights. This report is the latest addition to Market Research Hub’s ever growing repository
Less number of trypanosomes make detection difficult
Diagnosis of African Trypanosomiasis include presence of trypanosomes in different mediums including blood, cerebrospinal fluid and lymph node aspirates. Detection is generally difficult as very less number of trypanosomes are present in any fluid or blood. Stained blood films are obtained for better diagnosis. Various concentrated approaches including miniature anion exchange columns are employed to detect African Trypanosomiasis.
Control of African Trypanosomiasis primarily includes elimination of hosts from human settlements. Tsetse files’ habitats are destroyed as a precaution. Chemotherapeutic treatment is popular for African Trypanosomiasis. It is found to be successful in reducing the infection cases.
African Trypanosomiasis pipeline review: Report Synopsis
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African Trypanosomiasis pipeline review: Research Methodology
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