Published on : Sep 24, 2019
Albany, New York, September 24, 2019: Mycoplasmas are microbial contaminants of cell cultures capable of changing cell metabolism and phenotype. Mycoplasma testing is important as there are possibilities of mycoplasma contamination in cell-derived biological and biopharmaceutical products used in therapeutic treatment. This in turn poses safety risk in health sector and business risk for biopharmaceutical companies.
Mycoplasma infection can prevail for a long period of time before detection. Mycoplasma testing is necessary to inspect the presence of mycoplasma at the onset of infection. Testing involves culture of mycoplasmas in agar plates, indicator cells and broth. Mycoplasma testing is segmented into two methods, namely, direct and indirect method. Direct method deals with detecting presence of mycoplasma colony on agar, whereas indirect method measures gene product linked to mycoplasma.
These insights are according to the intelligence report, titled, “Global Mycoplasma Testing Market 2019-2023, Trends and Forecast Report,” which has been freshly added to Market Research Hub’s (MRH) over-arching repository.
Hundred percent elimination of mycoplasma is practically impossible, generating need of periodic examination through mycoplasma tests. These testing methods are still underdeveloped and are being worked upon. Mycoplasma testing methods can be broadly divided into microbial culture method, DNA straining by fluorochromes method and polymerase chain reaction method.
DNA staining by flurochromes requires expertise
Microbiological culture is the officially approved mycoplasma test that involves cell culture supernatant being added to liquid medium to initiate mycoplasma culture. This method is considered a gold standard in mycoplasma contamination detection as it gives positive results of contamination irrespective of the species and origin of plasma.
DNA staining by fluorochromes is a rapid and easy mycoplasma test, though the interpretation of result is difficult. The staining result can be misinterpreted if the cell culture is not in good condition. Polymerase chain reaction is efficient, fast, easy and reliable mycoplasma test. 16S rRNA molecules are detected in the most common species of cell cultures contaminated by mycoplasma.
Key players profiled in global mycoplasma testing ecosystem are Merck Kgaa, Lonza group, Thermo Fisher Scientific, American Type Culture Collection, Invivogen, Promocell, Wuxi Apptec, Norgen Biotek, SGS and Charles River Laboratories International.
Global mycoplasma testing Market: Report Synopsis
Quantitative and qualitative assessment exhort intelligence and overarching report on the Global mycoplasma testing Market. Further, the report thoroughly delineates various aspects of the market that will potentially have considerable influence on the development of the Global mycoplasma testing Market. As such, those aspects incorporate drivers, trends, restraints, and opportunities. Furthermore, the report elucidates segregation of the market that provides an exhaustive analysis on mycoplasma testing.
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Global mycoplasma testing Market: Research Methodology
Primary sources and secondary sources propel intelligence report on Global mycoplasma testing Market that provide deep dive analysis on the market. As such, the report provides reliable and unbiased projections, and assessments which have palpable impact on the market size and historical data. Besides, the report also counts on primary sources which hinges upon in-depth and intelligent analysis from well-grounded and reliable experts, telephonic interview, and a thorough assessment from surveys and seasoned analyst.
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